NzanzuKikuhe Jason
Makerere University, College of Health Sciences; Department of Ear, Nose and Throat, Uganda
Title: Hearing loss among children with sickle cell anaemia in uganda, a case control study
Biography:
Dr Nzanzu Kikuhe Jason has his expertise in research and evaluation in primary healthcare. He has also expertise in clinical practice medicine and teaching(otorhinolaryngology). He has built his expertise after years of experience in research, evaluation, teaching and administration both in hospital and education institutions. He speaks fluently and writes perfectly in French and English
Abstract:
ABSTRACT Aim: A case control was carried out to study the prevalence, the pattern and associated factors of hearing loss among Ugandan children with sickle cell anemia. Material and methods: One hundred and thirty-two children known sickle cell and one hundred thirty aged matched non SCA controls were recruited after medical ethics committee approval and an informed consent. To obtain information on sociodemographic characteristics, history and examination of the participants, a structured questionnaire was administered. A pure tone audiometry (PTA) was used to assess the hearing in a sound treated room. Results: Twenty two of the children had hearing impairement compared to 6 controls. Prevalence of hearing loss found among children with SCA was 17% but in the control group the prevalence found was 5%. Sensorineural hearing loss (SNHL) affected 39%, conductive (CHL) 25% and mixed (MHL) 14% among cases compared to CHL 7%, SNHL 7% and MHL 7% among the controls. The hearing loss varied from mild to moderate (95%). All sickle cell children had high frequency hearing loss. There was a statistically significant association of hearing loss and neurologic motor deficit. Conclusion: Sickle patients are at risk of developing hearing loss as the studydemonstrated difference in hearing threshold in children living with sickle cell anemia and the controls. High frequencies were more affected. Neurologic motor deficit was highly associated with hearing loss among patients with SCA compared to controls.